Basically the HTC Inspire is more complicated version of the European Desire. Rooting the Inspire is actually a very easy process although it can be overwhelming to look at when your reading it from the developer (let’s face it he is smarter when it comes to this than we are or we wouldn’t need his method to root). It is best to make sure you do this on a PC that does not and has not ever been associated with any mobile devices to ensure everything goes smooth.
Pre-Requisites to Root the HTC Inspire with HackAce:
How to Root the HTC Inspire easily with HackAce:
What happends next?
Basically HackAce will move the required files to your HTC Inspire and temporarily root the device. This will then turn your SDcard into a goldcard, set radio s-off and set SuperCID. As a bonus it will also remove the SIMLOCK during this process and it will install ClockworkMod Recovery and perm root the Inspire. Last it will Install Superuser for root priveledge management. Your Inspire will reboot several times during the root process and is normal.
If this tool is helpful to you then you should think about donating to the developer. Also there is more information if you run into any issues during this process via the reference link below. We are in no way responsible for your use of this information although will gladly answer any questions you have via comments below.
Reference: XDA Developers